61869-08-7,With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.61869-08-7,(3S,4R)-3-((Benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine,as a common compound, the synthetic route is as follows.
1.0 g of oily paroxetine free base and 1.24 g of cholic acid were completely dissolved in 20 mL of methanol while heating to 40 C. with shaking for 2 hours. The solvent was removed under reduced pressure, and then the residue was dried under vacuum, yielding 2.2 g of solid paroxetine cholate as a white powder. ; EXAMPLE 3 1.0 g of oily paroxetine free base and 1.24 g of cholic acid were completely dissolved in 10 mL of methanol while heating to 40 C. with shaking for one hour. The solution was slowly added dropwise to 100 mL of ethyl ether to precipitate a solid, stirred at 0 C. for 3 hours, and filtered. The filtered residue was washed with 30 mL of ethyl ether, and dried under vacuum to yield 1.89 g of solid paroxetine cholate as a light gray powder.
As the paragraph descriping shows that 61869-08-7 is playing an increasingly important role.
Reference：
Patent; Lee, Sang Joon; Shin, Hee Jong; Ki, Min Hyo; Lee, Su Kyoung; Kim, Bok Young; Lee, Hong Woo; US2006/63747; (2006); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem