358789-72-7, 4-((1-Methylpiperidin-4-yl)oxy)aniline is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Example No. 163Preparation of (8- ethoxy-2H-pyrazolo [3, 4-c] quinolin-4-yl) – [4- (l-methyl-piperidin-4-yloxy) -phenyl] -amine4-chloro-8-methoxy-2- (4 -methoxybenzyl) -2H-pyrazolo [3 , 4 – c]quinoline (0.16 mmol) and 4- ( (l-methylpiperidin-4- yl) oxy) aniline (2 eq.,0.3 mmol) were suspended in MeOH (dry, 3mL) in a microwave vial (2-5mL) , HC1 in dioxane (4M, 3 drops) was added. The reaction mixture was irradiated in a microwave reactor for 5 min at 140C. The reaction mixture was evaporated and used without further purification. The residue was dissolved in TFA (3mL) . The reaction mixture was irradiated in a microwave reactor for 5 min at 140C. The reaction mixture was concentrated and purified by semi- preparative HPLC-MS and freeze dried from water/t-BuOH 4/1. exact mass: 403.2399 g/molHPLC-MS: analytical method Crt: 1.460 min – found mass: 404.2 (m/z+H), 358789-72-7
358789-72-7 4-((1-Methylpiperidin-4-yl)oxy)aniline 16765164, apiperidines compound, is more and more widely used in various fields.
Reference：
Patent; ORIGENIS GMBH; ALMSTETTER, Michael; THORMANN, Michael; TREML, Andreas; KOESTLER, Roland; YEHIA, Nasser; WO2012/143143; (2012); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem