25504-47-6, Methyl 2-oxopiperidine-4-carboxylate is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Add Lawesson’s reagent (9.2 g, 22.7 mmol) to a solution of methyl2-oxopiperidine-4-carboxylate (6.5 g, 41.4 mmol) in toluene (83 mL) and heat to reflux for 2 hours. Cool the solution and concentrate to dryness under reduced pressure. Purify the residue by flash chromatography on silica gel, eluting with ethyl acetate :dichloromethane (gradient 5-15percent) to afford the title compound (6.95 g). lH NMR (CDCI3) delta 1.97 (m, 1H), 2.17 (m, 1H), 2.78 (m, 1H), 3.03 (m, 1H), 3.24 (m, 1H), 3.39 (m, 1H), 3.49 (m, 1H), 3.72 (s, 3H), 8.48 (bs, 1H)., 25504-47-6
The synthetic route of 25504-47-6 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; ELI LILLY AND COMPANY; PRIETO, Lourdes; TABOADA MARTINEZ, Lorena; WO2011/82010; (2011); A1;,
Piperidine – Wikipedia
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