20691-89-8, 1-Methyl-4-piperidinemethanol is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Example 57 ; 3-methoxv-4-I(I -methvlDiDeridin-4-Vl)methoxvlbenzonitrile; 53.3 ml of 1 N sodium bis (trimethylsilyl)amide added to a stirred solution of 6.63 g (51.3 mmol) of (1-methyl-piperidin-4-yl)-methanol in 14 ml of THF. After 20 minutes, solid 4-fluoro-3-methoxy benzonitrile was added. The mixture was refluxed for 20 minutes, cooled to room temperature and poured into water. The mixture was extracted with ethyl acetate. The organic extracts were dried over magnesium sulfate. The solvent was removed and the residue was recrystallized from ethyl acetate-hexanes yielding 8.9 g of the title compound as a white solid: mass spectrum (electrospray, m/e): M+H 261.2.
20691-89-8, 20691-89-8 1-Methyl-4-piperidinemethanol 271971, apiperidines compound, is more and more widely used in various fields.
Reference:
Patent; WYETH; WO2005/115145; (2005); A2;,
Piperidine – Wikipedia
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