1181267-36-6, tert-Butyl 4-(1-(2-ethoxyethyl)-1H-benzo[d]imidazol-2-yl)piperidine-1-carboxylate is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
1181267-36-6, 1) In a three-necked bottle, 100 g of intermediate II was added in sequence, 250 ml of tetrahydrofuran was added, and the reaction was cooled to 0 to 5 C, and 105 ml of concentrated hydrochloric acid was slowly added dropwise, and the mixture was stirred overnight; 2) The liquid phase is controlled to the raw material II <0.5%, and the post-treatment is started; 2) The solvent tetrahydrofuran was evaporated under reduced pressure, and then the mixture was evaporated to dryness. Combine the organic layers. Concentrated under reduced pressure to give the intermediate interrupter III, having a weight of 70.2g, a yield of 96%. The obtained intermediate III was subjected to high performance liquid chromatography analysis, and the spectrum is shown in Fig. 3. There are 5 peaks in the map, and the data is shown in Table 3.
The synthetic route of 1181267-36-6 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Chongqing Huabang Shengkai Pharmaceutical Co., Ltd.; Gao Hongsheng; Wang Haibo; Zhang Yueqin; Fu Yi; Sun Xiaolu; Huang Shanhua; Tang Chaojun; (12 pag.)CN109810093; (2019); A;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem