1180112-41-7, tert-Butyl 1,7-diazaspiro[3.5]nonane-7-carboxylate is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a solution of intermediate 343 (100 mg, 240.2 muiotaetaomicron, 1 eq) in CH3CN (5 mL) were added tert-butyl 1, 7-diazaspiro[3.5]nonane-7-carboxylate (109 mg, 480.5 muiotaetaomicron, 2 eq) and K2C03 (199 mg, 1.44 mmol, 6 eq). The mixture was stirred at 70 C for 15h. The mixture was extracted with EtOAc and the organic layer was concentrated to dryness. The crude was purified by TLC (EtOAc), to give intermediate 344 (40 mg, 54.4 muiotaetaomicron, 22.6% yield)., 1180112-41-7
The synthetic route of 1180112-41-7 has been constantly updated, and we look forward to future research findings.
Reference：
Patent; JANSSEN PHARMACEUTICA NV; BERTHELOT, Didier Jean-Claude; BREHMER, Dirk; BEKE, Lijs; BOECKX, An; DIELS, Gaston Stanislas Marcella; GILISSEN, Ronaldus Arnodus Hendrika Joseph; LAWSON, Edward Charles; PANDE, Vineet; PARADE, Marcus Cornelis Bernardus Catharina; SCHEPENS, Wim Bert Griet; SHOOK, Brian Christopher; THURING, Johannes Wilhelmus John F.; VIELLEVOYE, Marcel; SUN, Weimei; WU, Tongfei; MEERPOEL, Lieven; (244 pag.)WO2017/153186; (2017); A1;,
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