In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 67686-01-5, name is (1-Benzylpiperidin-4-yl)methanol, introducing its new discovery. HPLC of Formula: C13H19NO
Discovery of diarylurea P2Y1 antagonists with improved aqueous solubility
Preclinical data suggests that P2Y1 antagonists, such as diarylurea compound 1, may provide antithrombotic efficacy similar to P2Y 12 antagonists and may have the potential of providing reduced bleeding liabilities. This manuscript describes a series of diarylureas bearing solublizing amine side chains as potent P2Y1 antagonists. Among them, compounds 2l and 3h had improved aqueous solubility and maintained antiplatelet activity compared with compound 1. Compound 2l was moderately efficacious in both rat and rabbit thrombosis models and had a moderate prolongation of bleeding time in rats similar to that of compound 1.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 67686-01-5 is helpful to your research. HPLC of Formula: C13H19NO
Reference£º
Piperidine – Wikipedia,
Piperidine | C5H15235N – PubChem