Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Strassler, Christoph, once mentioned the application of 119515-38-7, Name is sec-Butyl 2-(2-hydroxyethyl)piperidine-1-carboxylate, molecular formula is C12H23NO3, molecular weight is 229.3159, MDL number is MFCD01756488, category is piperidines. Now introduce a scientific discovery about this category, Application In Synthesis of sec-Butyl 2-(2-hydroxyethyl)piperidine-1-carboxylate.
SYNTHESIS OF TRIPEPTIDES CONTAINING HETEROCYCLIC alpha-AMINO ACIDS BY USING HETEROSPIROCYCLIC 3-AMINO-2H-AZIRINES
By using the ‘azirine/oxazolone method’, di- and tripeptides containing six-membered heterocyclic 4-amino-4-carboxylic acids with a piperidine, tetrahydropyran or tetrahydrothiopyran ring have been synthesized. It has been shown that the corresponding heterospirocyclic 3-(N-methyl-N-phenylamino)-2H-azirines are suitable synthons for these heterocyclic alpha-amino acids. As expected, the presence of these alpha,alpha-disubstituted alpha-amino acids stabilizes beta-turn conformations in the prepared tripeptides of type Z-Phe-Xaa-Val-OR.
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Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem