A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 10310-21-1, Name is 2-Amino-6-chloropurine, molecular formula is C5H4ClN5. In an article, author is Guerola, Marta,once mentioned of 10310-21-1, Safety of 2-Amino-6-chloropurine.
Synthesis of substituted piperidines by enantioselective desymmetrizing intramolecular aza-Michael reactions
An organocatalytic enantioselective intramolecular aza-Michael reaction has been described for the first time in a desymmetrization process employing substrates different from cyclohexadienones. By using 9-amino-9-deoxy-epi-hydroquinine as the catalyst and trifluoroacetic acid as a co-catalyst, a series of enantiomerically enriched 2,5-and 2,6-disubstituted piperidines have been obtained in good yields and with moderate diastereoselectivity. Depending on the catalyst/co-catalyst loading ratio, either the major or the minor diastereoisomer of the final piperidine products was achieved with high levels of enantioselectivity. Finally, some mechanistic insights have been considered by means of theoretical calculations which were in agreement with the experimental results obtained in the desymmetrization reaction.
Interested yet? Keep reading other articles of 10310-21-1, you can contact me at any time and look forward to more communication. Safety of 2-Amino-6-chloropurine.
Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem