With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.79099-07-3,1-Boc-4-Piperidone,as a common compound, the synthetic route is as follows.
A solution of 4-oxo-1-piperidinecarboxylic acid 1,1-dimethylethyl ester (25 g, 126 mmol) and DMF-DMA (50 mL, 377 mmol) in 1,4-dioxane (200 mL) was heated at 100 C for 20 hours. Upon completion, the reaction mixture was concentrated under reducedpressure to yield the title compound, which was used without further purification.
As the paragraph descriping shows that 79099-07-3 is playing an increasingly important role.
Reference£º
Patent; E I DU PONT DE NEMOURS AND COMPANY; ZHANG, Weniming; (101 pag.)WO2016/164200; (2016); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem