With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.71233-25-5,1-tert-Butyl 4-ethyl 3-oxopiperidine-1,4-dicarboxylate,as a common compound, the synthetic route is as follows.,71233-25-5
G. 5-Amino-3,6-dihydro-2H-pyridine-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester (35a2) To a solution of 34a2 (24 g, 88.5 mmol) was added ammonium in EtOH (88 mL, 180 mmol, 2M). The reaction mixture was heated to 60 C for 3 h. The solvent was evaporated under reduced pressure to afford a yellow solid (23 g, 91.5percent). MS (ES+): m/z=271 (M+1)
The synthetic route of 71233-25-5 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Hurley, Timothy Brian; Lee, Kwangho; Peukert, Stefan; Wattanasin, Sompong; US2009/325948; (2009); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem