Simple exploration of 6-(Benzyloxy)-7H-purin-2-amine

Electric Literature of 19916-73-5, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 19916-73-5.

Electric Literature of 19916-73-5, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 19916-73-5, Name is 6-(Benzyloxy)-7H-purin-2-amine, SMILES is C3=NC1=C(C(=NC(=N1)N)OCC2=CC=CC=C2)[NH]3, belongs to piperidines compound. In a article, author is Ordonez, Paola E., introduce new discover of the category.

Synthesis, Crystallography, and Anti-Leukemic Activity of the Amino Adducts of Dehydroleucodine

Dehydroleucodine is a bioactive sesquiterpene lactone. Herein, four dehydroleucodine amino derivatives were synthesized using the amines proline, piperidine, morpholine, and tyramine, and spectroscopic methods and single-crystal X-ray diffraction unambiguously established their structures. The cytotoxic activity of these compounds was evaluated against eight acute myeloid leukemia cell lines, and their toxicity to peripheral blood mononuclear cells was also determined. The proline adduct was the most active compound, it showed anti-leukemic activity, upregulated heme oxygenase 1 (HMOX1) and the primary stress-inducible isoform of the heath shock 70 kDa protein 1 (HSPA1A), and downregulated NFkB1 transcription, it was also found to be about 270 times more water soluble than dehydroleucodine.

Electric Literature of 19916-73-5, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 19916-73-5.

Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem