3970-68-1, 4-Methylpiperidin-4-ol is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Example 13.1; 1-(4-{2-[6-(4-Methoxy-phenyl)-py?dazin-3-yloxy1-ethoxy)-benzyl)-4-methyl-piperidin-4-ol; 100 mg (0.285 mmol) 4-{2-[6-(4-Methoxy-phenyl)-pyridazin-3-yloxy]-ethoxy}-benzaldehyde (educt XII.1 ) and 35 mg (0.30 mmol) 4-methyl-pipeiotadin-4-ol are dissolved in 10 ml of THF and 0.20 ml cone, acetic acid are added. After 10 minutes 180 mg (0.855 mmol) sodium triacetoxyborohydride are added and the mixture is stirred for 20 hours at RT. After that time the mixture is filtered and the solvent is evaporated. The residue is purified by silica gel column chromatography with methylene chloride/methanol/ammonia (10:1 :0.1 ) as eluent. Yield: 50 mg (39% of theory),Rf value: 0.25 (silica gel, methylene chloride/methanol/ammonia = 10:1 :0.1 )EII mass spectrum: m/z = 450 [M+H]+
3970-68-1, The synthetic route of 3970-68-1 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG; WO2007/48802; (2007); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem