297172-16-8, (4-Methylpiperidin-4-yl)methanol is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
(4-methylpiperidin-4-yl)methanol (E4) (2.4 g, a mixture of the amino alcohol and NH4CO2H) was suspended in DCM (70 mL). Et3N (5 mL; 37.2 mmol) was then added followed by the drop-wise addition of ethyl chloroformate (1.05 mL, 13 mmol, 1.4 eq.). After 1 h at room temperature, 1N HCl (70 mL) was added and the layers were separated. The aqueous layer was extracted with DCM (70 mL) and the combined organic layers were dried over Na2SO4, filtered, and concentrated under high vacuum. The product (E5) (1.7 g) is obtained analytically pure as an oil and used without further purification. LC/MS m/z (M+1) 202.2, tR 1.89 minutes; (10-99% CH3CN-H2O gradient with 0.03% TFA, 5 min). 1H NMR (400 MHz, DMSO-d6) delta 4.05 (q, J=7.1 Hz, 2H), 3.66 (dt, J=13.6, 4.7 Hz, 2H), 3.32 (s, 2H), 3.11 (t, J=5.2 Hz, 1H), 3.11 (dd, J=23.9, 3.5 Hz, 1H), 1.44-1.37 (m, 3H), 1.26-1.22 (m, 2H), 1.19 (t, J=7.1 Hz, 3H), 0.93 (s, 3H).
297172-16-8, As the paragraph descriping shows that 297172-16-8 is playing an increasingly important role.
Reference：
Patent; Makings, Lewis R.; Blanco, Miguel Garcia-Guzman; Hurley, Dennis J.; Drutu, Ioana; Raffai, Gabriel; Bergeron, Daniele M.; Nakatani, Akiko; Termin, Andreas P.; Silina, Alina; US2008/15179; (2008); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem