In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 1000796-62-2, name is tert-Butyl 3-aminopiperidine-1-carboxylate hydrochloride, introducing its new discovery. Application In Synthesis of tert-Butyl 3-aminopiperidine-1-carboxylate hydrochloride
In oncology, the ?Warburg effect? describes the elevated production of energy by glycolysis in cancer cells. The ubiquitous and hypoxia-induced 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3) plays a noteworthy role in the regulation of glycolysis by producing fructose-2,6-biphosphate (F-2,6-BP), a potent activator of the glycolysis rate-limiting phosphofructokinase PFK-1. Series of amides and sulfonamides derivatives based on a N-aryl 6-aminoquinoxaline scaffold were synthesized and tested for their inhibition of PFKFB3 in vitro in a biochemical assay as well as in HCT116 cells. The carboxamide series displayed satisfactory kinetic solubility and metabolic stability, and within this class, potent lead compounds with low nanomolar activity have been identified with a suitable profile for further in vivo evaluation.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 1000796-62-2 is helpful to your research. Application In Synthesis of tert-Butyl 3-aminopiperidine-1-carboxylate hydrochloride
Reference：
Piperidine – Wikipedia,
Piperidine | C5H19169N – PubChem