Chemistry is traditionally divided into organic and inorganic chemistry. Application In Synthesis of 8-Boc-2,8-Diazaspiro[4.5]decane. The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 236406-39-6
A series of 3,4-dihydro-3-amino-2H-1-benzopyran derivatives were prepared in order to determine the necessary structural requirements for good affinity for 5-HT1A receptors and high selectivity versus other receptors.Modifications of the extracyclic amino substituents, the length of the alkyl side chains, and their substituents were explored.The best compounds (9g, 9k, 15b, 15d) possess imido or sulfonamido functional groups with a preferential length of four methylenes for the side chain.After resolution, the dextrorotatory enantiomers showed better affinity and se lectivity for 5-HT1A receptors.These compounds have been proven to be full agonists. 9g and its enantiomers showed anxiolytic activity in vivo in various comportemental models.The compound (+)-9g is currently under clinical investigation.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Application In Synthesis of 8-Boc-2,8-Diazaspiro[4.5]decane, you can also check out more blogs about236406-39-6
Reference：
Piperidine – Wikipedia,
Piperidine | C5H19859N – PubChem