Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， Application In Synthesis of 3-(Piperidin-4-ylmethyl)-1H-indole, Which mentioned a new discovery about 3515-49-9
Protein aggregation is a hallmark of several neurodegenerative diseases, including Alzheimer’s and Parkinson’s diseases. It has been shown that lysine residues play a key role in the formation of these aggregates. Thus, the ability to disrupt aggregate formation by covalently modifying lysine residues could lead to the discovery of therapeutically relevant antiamyloidogenesis compounds. Herein, we demonstrate that an ortho-iminoquinone (IQ) can be utilized to inhibit amyloid aggregation. Using alpha-synuclein and Abeta1-40 as model amyloidogenic proteins, we observed that IQ was able to react with lysine residues and reduce amyloid aggregation. We also observed that IQ reacted with free amines within the amyloid fibrils preventing their dissociation and seeding capacity.
Because enzymes can increase reaction rates by enormous factors and tend to be very specific, Application In Synthesis of 3-(Piperidin-4-ylmethyl)-1H-indole, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 3515-49-9
Reference：
Piperidine – Wikipedia,
Piperidine | C5H16939N – PubChem