A study on prescription pattern of chronic kidney disease in tertiary care hospital was written by Saraswathi Pravallika, M.;Sampreethi, H.;Anusha, C. H.;Rohini, K.;Shete, Shivkumar. And the article was included in European Journal of Biomedical and Pharmaceutical Sciences in 2021.Electric Literature of C32H39NO4 The following contents are mentioned in the article:
The aim of the present investigation is to study the prescription pattern of chronic kidney disease in tertiary care hospital. The objective of the study was to study the prescription patterns of drugs used in chronic kidney disease and other comorbid conditions and to identify which drug is mostly prescribed at that hospital. To assess the rationality of prescription. To evaluate the medication adherence in CKD patients. The study on prescribing pattern definitely improves the quality of prescription writing, so study of drug prescribing pattern is relevant in the present scenario. To evaluate the prevalence of correct dosing in chronic kidney diseases depending on renal function estimation This is a retrospective, prospective observational study conducted over a period of six months. The study was conducted at Medicine ward of GLENEAGLES AWARE GLOBAL HOSPITAL LB.NAGAR. Patients who admitted to Nephrol. department of the hospital during a six- month period from Oct. 2021 to March 2021 are enrolled. CKD patients visiting the nephrologists are evaluated, diagnosed and prescribed with suitable therapy. All necessary details were collected from patient demographics, prescription chart, lab data, progress chart, medical records, doctor’s notes, nursing notes using a suitable designed data collection form. One hundred one patients were included in the project; with a mean age of 62.5. ± 18 years. More than half of patients were male, 77(76.2%). The mean BMI was 26 ± 1.15 kg/ m2. The majority of patients were having normal weight 80 (79.2%), 15 (14.8%) patients had overweight, and obesity and only 6 (5.9%) patients were underweight. While 35 (34.6%) patients were smokers, 10 (9.9%) were ex-smokers and 56 (55.4%) patients were non- smokers. Anti- hypertensive agents are predominantly used among the patients. The most preferred options were beta blockers, calcium channel blockers and diuretics. Most of the physicians prescribed metoprolol (18.2%), amlodipine (38.3%), and cilnidipine (2%). Diuretics were the preferred option by the physician furosemide (92.3%), anti-platelets that are prescribed by the physicians are Aspirin (69.2%), clopidogrel (30.7%). Among the lipid lowering agents, atorvastatin (92.8%) was given to the most of the patients. sulbactam (20.4%), cefoperazone (20.4%), clarithromycin (10.25%), amoxycillin (10.25%) were mostly prescribed antibiotics in the study. The study concluded that most of the patients included in the study were suffering from chronic kidney disease. These may be due to their food habits, smoking, less exercise and poor health hygiene. The maximum number of patients was male; it may be due to smoking and alc. habits. Comorbidities such as hypertension, hyperglycemia, albuminuria, renal structure, and sex hormones, have been reported to have different effects on males and females. Thus, CKD progression may differ depending on sex. Early recognition with timely initiation of treatment in collaboration with nephrologists will improve the care for CKD patients. Thus, physicians and Nephrologists play an important outcome in patients with CKD. This study involved multiple reactions and reactants, such as 2-(4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butyl)phenyl)-2-methylpropanoic acid (cas: 83799-24-0Electric Literature of C32H39NO4).
2-(4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butyl)phenyl)-2-methylpropanoic acid (cas: 83799-24-0) belongs to piperidine derivatives. Piperidine is a saturated organic heteromonocyclic parent, an azacycloalkane, a secondary amine and a member of piperidines. Fluorinated piperidines are also the subject of continued interest in medicinal chemistry, for example in the synthesis of selective dipeptidyl peptidase II (DPP II) inhibitors. Piperidine derivatives are also used in solid-phase peptide synthesis (SPPS) and many degradation reactions.Electric Literature of C32H39NO4
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem