Rele, Rajan V. et al. published their research in Journal of Chemical and Pharmaceutical Research in 2016 | CAS: 153439-40-8

2-(4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butyl)phenyl)-2-methylpropanoic acid hydrochloride (cas: 153439-40-8) belongs to piperidine derivatives. Piperidine and its derivatives have become increasingly popular in many synthetic schemes. Fluorinated piperidines are also the subject of continued interest in medicinal chemistry, for example in the synthesis of selective dipeptidyl peptidase II (DPP II) inhibitors. Piperidine derivatives are also used in solid-phase peptide synthesis (SPPS) and many degradation reactions.HPLC of Formula: 153439-40-8

UV spectrophotometric derivative methods for estimation of fexofenadine hydrochloride in bulk drug and pharmaceutical dosage form was written by Rele, Rajan V.. And the article was included in Journal of Chemical and Pharmaceutical Research in 2016.HPLC of Formula: 153439-40-8 This article mentions the following:

Simple and precise UV spectrophotometric methods by second and third order derivative have been developed and validated for the estimation of fexofenadine hydrochloride in bulk and its tablet formulation. The standard and sample solutions of fexofenadine hydrochloride were prepared in 0.1 N Hydrochloric acid. Fexofenadine hydrochloride was estimated at 215 nm for the second order derivative and 233.7 nm for third order derivative resp. Beer’s law was obeyed in the concentration range of 1 to 14 渭g / ml with coefficient of correlation values were 0.9992 for second order derivative method and 0.9997 for third order derivative method resp. These methods were tested and validated for various parameters according to ICH guidelines. The precision expressed as relative standard deviation were of 0.8908 % and 1.152% for the above two methods resp. The proposed methods were successfully applied for the determination of fexofenadine hydrochloride in pharmaceutical formulation. Results of the anal. were validated statistically and were found to be satisfactory. The proposed methods are simple, easy to apply, low-cost and require relatively inexpensive instruments. In the experiment, the researchers used many compounds, for example, 2-(4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butyl)phenyl)-2-methylpropanoic acid hydrochloride (cas: 153439-40-8HPLC of Formula: 153439-40-8).

2-(4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butyl)phenyl)-2-methylpropanoic acid hydrochloride (cas: 153439-40-8) belongs to piperidine derivatives. Piperidine and its derivatives have become increasingly popular in many synthetic schemes. Fluorinated piperidines are also the subject of continued interest in medicinal chemistry, for example in the synthesis of selective dipeptidyl peptidase II (DPP II) inhibitors. Piperidine derivatives are also used in solid-phase peptide synthesis (SPPS) and many degradation reactions.HPLC of Formula: 153439-40-8

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem