Chemistry can be defined as the study of matter and the changes it undergoes. You’ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 79725-98-7, Name is (4-Oxo-5-(palmitoyloxy)-4H-pyran-2-yl)methyl palmitate, molecular formula is , belongs to piperidines compound. In a document, author is Feliciano, Alberto, Safety of (4-Oxo-5-(palmitoyloxy)-4H-pyran-2-yl)methyl palmitate.
Synthesis of novel 2,5-substituted p-aminophenols and 2,5-substituted p-quinones in a one-pot reaction between alpha- alkoxyvinyl(ethoxy)carbene complexes, amines and alkynes
The synthesis of novel p-aminophenols 19a-o and p-quinones 21a-i was carried out by an aminolysis reaction/[3 + 2+1] cycloaddition cascade process of alpha-alkoxyvinyl (ethoxy) Fischer carbene complexes of group 6 metals (M = Cr, Mo, W), primary and secondary amines and terminal alkynes. The multicomponent reaction of carbenes la-c with morpholine (6a) and piperidine (6c), respectively, and terminal alkynes 17a-d only afforded the 4-aminophenols 19a-o in moderated yields. The products bore the terminal alkyne substituent at the ortho position of the hydroxyl group. These one-pot reactions showed highly regio- and chemoselectivity, favoring the benzannulation products. When carbene complexes la-c were reacted with primary amines 10a-c and alkynes 17a-c under the same conditions, the cascade process led to the formation of p-quinones 21a-21i, in moderate yields. The regiochemistry of the compounds was established by NOE experiments, and the structures of morpholinocarbene 7a, p-aminophenols 19b, 19d and p-quinone 21b were confirmed by single-crystal X-ray diffraction. (C) 2020 Elsevier B.V. All rights reserved.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 79725-98-7, in my other articles. Safety of (4-Oxo-5-(palmitoyloxy)-4H-pyran-2-yl)methyl palmitate.
Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem