Application of 41661-47-6, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 41661-47-6, Name is 4-Piperidinone,introducing its new discovery.
Aryl- and heteroarylzinc pivalates can be aminated with O-benzoylhydroxylamines at 25 C within 2?4 h in the presence of 2.5?5.0 % CoCl2?2 LiCl to furnish the corresponding tertiary arylated or heteroarylated amines in good yields. This electrophilic amination also provides access to diarylamines and aryl(heteroaryl)amines. A new tuberculosis drug candidate (Q203) was prepared in six steps and 56 % overall yield by using this cobalt-catalyzed amination as the key step.
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Reference：
Piperidine – Wikipedia,
Piperidine | C5H356N – PubChem