Chemistry is traditionally divided into organic and inorganic chemistry. Application In Synthesis of 1-Benzyl-4-methylpiperidin-3-one. The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 32018-96-5
The invention discloses a method for supporting france for cloth starting material N – ((3 R, 4 R) – 4 – methyl – 1 – benzyl – 3 – piperidinyl) – N – methyl – 7 – paratoluene sulfonyl – 7 H – pyrrolo [2, 3 – D] pyrimidine – 4 – amine (I) synthetic method, specific steps are as follows: to 4 – methyl pyridine as the starting material, with the benzyl chloride undergo nucleophilic substitution by the 4 – methyl – 1 – phenylmethyl – pyridine hydrochloride, under the action of the sodium borohydride reduction reaction, borohydrite – oxidation reaction, hydroxy oxidation, the introduction of the reductive amination of the stereo selectivity of the two chiral center, through a readily available and inexpensive chiral acid (L – DTTA) splitting, to obtain optically pure intermediates (3 R, 4 R) – (1 – benzyl – 4 – methyl – piperidin – 3 – yl) – methylamine, and finally with the 4 – chloro pyrrolo pyrimidine condensation is obtained. The whole method raw materials are easy, simple operation, after treatment is easy, and the cost is low. (by machine translation)
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Application In Synthesis of 1-Benzyl-4-methylpiperidin-3-one, you can also check out more blogs about32018-96-5
Reference：
Piperidine – Wikipedia,
Piperidine | C5H15118N – PubChem