Synthetic Route of 27578-60-5, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 27578-60-5, Name is N-(2-Aminoethyl)piperidine, molecular formula is C7H16N2. In a Article£¬once mentioned of 27578-60-5
CCR2 receptor antagonists: Optimization of biaryl sulfonamides to increase activity in whole blood
A series of biarylsulfonamides was identified as hCCR2 receptor antagonist but suffered from high plasma protein binding resulting in a >100 fold shift in activity in a functional GTPgammaS assay run in tandem in the presence and absence of human serum albumin. Introduction of an aryl amide with ethylenediamine linker led to compounds with reduced shifts and improved activity in whole blood.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Synthetic Route of 27578-60-5, you can also check out more blogs about27578-60-5
Reference£º
Piperidine – Wikipedia,
Piperidine | C5H4765N – PubChem