Properties and Exciting Facts About 252882-61-4

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Electric Literature of 252882-61-4, you can also check out more blogs about252882-61-4

Electric Literature of 252882-61-4, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 252882-61-4, Name is Spiro[indoline-3,4′-piperidin]-2-one, molecular formula is C12H14N2O. In a Article，once mentioned of 252882-61-4

We report the synthesis of rigid spirocyclic systems as conformationally constrained variants of the Ala-Phe-NH2 dipeptide amide C-terminus of the calcitonin gene-related peptide (CGRP). CGRP receptor antagonists containing these moieties displayed potent affinity, functional antagonism and excellent oxidative stability. Structure-activity relationship studies demonstrated the relative importance of hydrogen bond donor/acceptor functionalities and the preferred orientation of an aromatic ring. Antagonists showed potent and full reversal of CGRP-induced dilation of ex vivo human intracranial arteries.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Electric Literature of 252882-61-4, you can also check out more blogs about252882-61-4

Reference：
Piperidine – Wikipedia,
Piperidine | C5H15077N – PubChem