Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, Recommanded Product: 201341-05-1, 201341-05-1, Name is Tenofovir disoproxil, SMILES is O=C(OC(C)C)OCOP(OCOC(OC(C)C)=O)(CO[C@H](C)CN1C=NC2=C(N)N=CN=C12)=O, belongs to piperidines compound. In a document, author is Islam, Mohammad Jahirul, introduce the new discover.
Sterically encumbered dianionic dicarboranyl pincer ligand (C5H3N)(C2B10H11)(2) and its CNC Nickel(II) complex
The novel 2,6-bis(carborane) pyridine (C5H3N)(C2B10H11)(2) ligand precursor containing two icosahedral carborane clusters attached to the pyridine ring was synthesized by the SNAr reaction between 2,6-difluoropyridine and lithiated ortho-carborane LiC2B10H11. Lithiation of the proligand at carbon atoms of carborane cages and the subsequent reaction with Ni(PPh3)(2)Cl-2 afforded the square-planar Ni(II) pincer complex {(C5H3N)(C2B10H10)(2)} Ni(CH3CN). X-ray single crystal diffraction revealed extreme steric hindrance around the metal center in the complex imposed by two carboranyl groups in the rigid pincertype framework, which was also manifested by the high value of the ligand buried volume % V-bur = 70.6%. The title pincer complex {(C5H3N)(C2B10H10)(2)} Ni(CH3CN) was found to be a competent catalyst for nucleophilic addition of piperidine to acetonitrile. (C) 2017 Elsevier B.V. All rights reserved.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 201341-05-1. Recommanded Product: 201341-05-1.
Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem