Padungros, Panuwat’s team published research in Journal of Organic Chemistry in 79 | CAS: 4972-31-0

Padungros, Panuwat published the artcileSynthesis and Reactivity of 4′-Deoxypentenosyl Disaccharides, Formula: C11H15NOS, the publication is Journal of Organic Chemistry (2014), 79(11), 4878-4891, database is CAplus and MEDLINE.

4-Deoxypentenosides (4-DPs) are versatile synthons for rare or higher-order pyranosides, and they provide an entry for structural diversification at the C5 position. Previous studies have shown that 4-DPs undergo stereocontrolled DMDO oxidation; subsequent epoxide ring-openings with various nucleophiles can proceed with both anti or syn selectivity. Here, we report the synthesis of α- and β-linked 4′-deoxypentenosyl (4′-DP) disaccharides, and we investigate their post-glycosylation C₅‘ additions using the DMDO oxidation/ring-opening sequence. The α-linked 4’-DP disaccharides were synthesized by coupling thiophenyl 4-DP donors with glycosyl acceptors using BSP/Tf₂O activation, whereas β-linked 4′-DP disaccharides were generated by the decarboxylative elimination of glucuronyl disaccharides under microwave conditions. Both α- and β-linked 4′-DP disaccharides could be epoxidized with high stereoselectivity using DMDO. In some cases, the α-epoxypentenosides could be successfully converted into terminal L-iduronic acids via the syn addition of 2-furyl-zinc bromide. These studies support a novel approach to oligosaccharide synthesis, in which the stereochem. configuration of the terminal 4′-DP unit is established at a post-glycosylation stage.

Journal of Organic Chemistry published new progress about 4972-31-0. 4972-31-0 belongs to piperidines, auxiliary class Piperidine,Benzene, name is 1-(Phenylsulfinyl)piperidine, and the molecular formula is C11H15NOS, Formula: C11H15NOS.

Referemce:
https://en.wikipedia.org/wiki/Piperidine,
Piperidine | C5H11N – PubChem