Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 88495-54-9, Name is (S)-1-(tert-Butoxycarbonyl)piperidine-3-carboxylic acid, molecular formula is C11H19NO4, belongs to piperidines compound. In a document, author is Gandhi, Divyani, introduce the new discover, Category: piperidines.
Synthesis, characterization and evaluation of novel benzothiazole clubbed chromene derivatives for their anti-inflammatory potential
A series of chromene derivatives (5a-f) were prepared by multistep synthesis process using 2-[3-phenyl prop-2-ene nitrile] 1,3-benzothiazole and dimedone using piperidine as catalyst in ethanol. The reaction was found to proceed via Knoevenagel condensation of aldehydes with benzothiazole, followed by the elimination to afford the 2-(benzo[d]thiazol-2-yl)-3-(aryl)acrylonitrile, which then undergoes Michael addition with 5,5-dimethyl-1,3-cyclohexanedione, followed by intramolecular O-cyclization to give the products. The structures of all novel constructed derivatives were corroborated by elemental analysis and spectral data (FT-IR, H-1-NMR, C-13-NMR and Mass). Subsequently, the compounds were tested for their in-vivo anti-inflammatory activity. This study revealed that these synthesized derivatives tend to have significantly anti inflammatory activity and shall prove as structural templates in the design and development of new anti inflammatory drugs. [GRAPHICS] .
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 88495-54-9. Category: piperidines.
Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem