Heterocycle-derived β-S-enals as bifunctional linchpins for the catalytic synthesis of saturated heterocycles was written by Niu, Jingze;Willis, Michael C.. And the article was included in Organic Chemistry Frontiers in 2016.Application of 33439-27-9 This article mentions the following:
We demonstrated how heterocycle-derived β-S-enals can be employed as bifunctional substrates in a cascade of two rhodium-catalyzed C-C bond forming reactions to deliver substituted heterocyclic products. A single rhodium-catalyst, generated in situ from a com. salt and ligand combination, was used to promote both an initial alkene or alkyne hydroacylation reaction, and then a Suzuki-type cross-coupling, resulting in a three-component assembly of the targeted heterocycles. Substrates based on N-, O- and S-heterocycles were included, as were a range of alkenes, alkynes and boronic acid derivatives In the experiment, the researchers used many compounds, for example, 1-Tosylpiperidin-4-one (cas: 33439-27-9Application of 33439-27-9).
1-Tosylpiperidin-4-one (cas: 33439-27-9) belongs to piperidine derivatives. Piperidine is a saturated organic heteromonocyclic parent, an azacycloalkane, a secondary amine and a member of piperidines. Piperidine derivatives bearing a masked aldehyde function in the ε-position are easily transformed into quinolizidine compounds through intramolecular reductive amination.Application of 33439-27-9
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem