Electric Literature of 4727-72-4, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 4727-72-4, Name is 1-Benzylpiperidin-4-ol, SMILES is C2=C(CN1CCC(O)CC1)C=CC=C2, belongs to piperidines compound. In a article, author is Smullen, Shaun, introduce new discover of the category.
Chemical synthesis of febrifugine and analogues
The quinazolinone-containing 2,3-disubstituted piperidines febrifugine and isofebrifugine have been the subject of significant research efforts since their occurrence in Dichroa febrifuga and their anti-malarial actions were first described in the late 1940s. Subsequently they have also been shown to be present in other plants belonging to the hydrangea family and various analogues of febrifugine have been prepared in attempts to tune biological properties. The most notable analogue is termed halofuginone and a substantial body of work now demonstrates that this compound possesses potent human disease relevant activities. This review focuses on the literature associated with efforts dedicated towards uncovering the structures of febrifugine and isofebrifugine, the development of practical methods for their synthesis and the syntheses of structural analogues. (C) 2018 Elsevier Ltd. All rights reserved.
Electric Literature of 4727-72-4, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 4727-72-4.
Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem