With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.72551-53-2,Ethyl 1-benzylpiperidine-3-carboxylate,as a common compound, the synthetic route is as follows.
72551-53-2, EXAMPLE 35 Preparation of ethyl 1-Benzyl-3-piperidinecarboxylate 1-Methiodide ethyl 1-benzyl-3-piperidinecarboxylate (590.6 mg; 2.39 mmol) was dissolved in diethyl ether (50 ml), and methyl iodide (2 ml) was added.. This mixture was allowed to stir at ambient temperature for 3 days and was then heated to reflux for 23 hours.. The precipitate was filtered, washed with fresh diethyl ether, and then dried under reduced pressure at ambient temperature, giving ethyl 1-benzyl-3-piperidinecarboxylate 1-methiodide (340.9 mg) as an off white solid. MS m/z (positive ion) 263 (MH+; 30), 262 (M+; 100).
The synthetic route of 72551-53-2 has been constantly updated, and we look forward to future research findings.
Reference：
Patent; Eli Lilly and Company; US6664271; (2003); B1;,
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