Electric Literature of C3F9FeO9S3. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: Iron(III) trifluoromethanesulfonate, is researched, Molecular C3F9FeO9S3, CAS is 63295-48-7, about Nitromethane as a nitrogen donor in Schmidt-type formation of amides and nitriles. Author is Liu, Jianzhong; Zhang, Cheng; Zhang, Ziyao; Wen, Xiaojin; Dou, Xiaodong; Wei, Jialiang; Qiu, Xu; Song, Song; Jiao, Ning.
The Schmidt reaction has been an efficient and widely used synthetic approach to amides and nitriles since its discovery in 1923. However, its application often entails the use of volatile, potentially explosive, and highly toxic azide reagents. Here, we report a sequence whereby triflic anhydride and formic and acetic acids activate the bulk chem. nitromethane to serve as a nitrogen donor in place of azides in Schmidt-like reactions. This protocol further expands the substrate scope to alkynes and simple alkyl benzenes for the preparation of amides and nitriles.
This compound(Iron(III) trifluoromethanesulfonate)Electric Literature of C3F9FeO9S3 was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.
Reference:
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