61869-08-7,With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.61869-08-7,(3S,4R)-3-((Benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine,as a common compound, the synthetic route is as follows.
1.0 g of oily paroxetine free base and 1.24 g of cholic acid were completely dissolved in a mixed solvent of ethanol (20 mL) and isopropyl acetate (30 mL) while heating to 50 C. with shaking for 2 hours. The solution was allowed to stand at -20 C. for 48 hours, filtered, and dried under vacuum to yield 1.9 g of solid paroxetine cholate as a light gray powder.
The synthetic route of 61869-08-7 has been constantly updated, and we look forward to future research findings.
Reference：
Patent; Lee, Sang Joon; Shin, Hee Jong; Ki, Min Hyo; Lee, Su Kyoung; Kim, Bok Young; Lee, Hong Woo; US2006/63747; (2006); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem