New learning discoveries about 479630-08-5

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479630-08-5, 1-Boc-4-(2-Ethoxycarbonyl-acetyl)piperidine is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Compound 5 (15 g, 45 mmol) was dissolved in anhydrous ethanol (400 mL) with compound 6 (9.45 g, 49.5 mmol), followed by addition of trifluoroacetic acid (20 mL) and heating at 80 C for 12 hours. Cool to room temperature and spin the solvent. The reaction mixture was diluted with water (100 mL), extracted with 1 M NaOH, and extracted with ethyl acetate (3×200 mL). The extract was dried over anhydrous sodium sulfate, filtered and dried with methanol: dichloromethane = 1:20 Compound 7 (13. 82 g, 72%) was isolated.

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Reference£º
Patent; HU, XIANMING; HONG, XUECHUAN; WANG, HONGBO; ZHU, XI; DING, MINGMIN; L, GUANGYAO; ZHANG, JIANQIAO; WEN, MENG; QU, CHUNRONG; ZHU, JINMEI; (14 pag.)CN104292233; (2016); B;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem