3612-20-2, 1-Benzylpiperidin-4-one is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Step A 1-benzyl-4-(methylamino)piperidine A solution of 1 mol of N-benzylpiperid-4-one in 2200 cm3 of isopropanol is cooled to 18 C. A freshly prepared solution of 3 mol of methylamine in 300 cm3 of methanol is added to the first solution. The mixture is left at that temperature for one hour. 1.66 mol of sodium hydroxide in the form of pellets are added. 1.37 mol of sodium borohydride are added at a constant temperature of 18 C. The mixture is allowed to return to room temperature and then the reagents are left in contact for 12 hours. The solvents are evaporated, and the residue is taken up in ether and then washed with water. Drying and evaporation yield an oil which is the desired compound. Yield: 78%., 3612-20-2
3612-20-2 1-Benzylpiperidin-4-one 19220, apiperidines compound, is more and more widely used in various fields.
Reference:
Patent; Adir et Compagnie; US5298503; (1994); A;,
Piperidine – Wikipedia
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