309962-63-8, (S)-tert-Butyl methyl(piperidin-3-yl)carbamate is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
A solution of 4-(6-fluoropyridin-3-yl)-6-(l-methyl-lH-pyrazol-4-yl)pyrazolo[l,5 a]pyrazine-3-carbonitrile (Intermediate P7; 0.100 g, 0.313 mmol) in DMSO (6.26 mL) was treated with (S)-tert-butyl methyl(piperidin-3-yl)carbamate (0.268 g, 1.25 mmol) and K2CCb(s) (0.173 g, 1.25 mmol) and stirred overnight at 110 C. After cooling to ambient temperature, the reaction mixture was diluted with water (10 mL) and extracted with DCM (4 x 10 mL) in a PS Frit. The combined organic extracts were concentrated in vacuo, and purified by C18 reverse phase chromatography (using 0-60% ACN/water as the gradient eluent) to afford the title compound (106 mg, 66% yield). MS (apci) m/z = 514.2 (M+H).
309962-63-8, 309962-63-8 (S)-tert-Butyl methyl(piperidin-3-yl)carbamate 28875358, apiperidines compound, is more and more widely used in various fields.
Reference£º
Patent; ANDREWS, Steven W.; BLAKE, James F.; HAAS, Julia; JIANG, Yutong; KOLAKOWSKI, Gabrielle R.; MORENO, David A.; REN, Li; WALLS, Shane M.; (421 pag.)WO2018/136661; (2018); A1;,
Piperidine – Wikipedia
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