One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time. 179474-79-4, Name is 1-(3-Methoxypropyl)piperidin-4-amine, formurla is C9H20N2O. In a document, author is Bhuma, Naresh, introducing its new discovery. Product Details of 179474-79-4.
Fluorinated piperidine iminosugars and their N-alkylated derivatives: Synthesis, conformational analysis, immunosuppressive and glycosidase inhibitory activity studies
The fluorinated piperidine iminosugars 2a-4a and their N-octyl and N-decyl derivatives 2b,c-4b,c were synthesized from D-mannoseio-xylose using nucleophilic fluorination as the key step. The conformation of iminosugars 2/3, either C-2(5) or C-5(2), was assigned based on the H-1 NMR studies at different pH. immunomodulatory activity of 2a,c-4a,c was examined using Mixed Lymphocyte Reaction (MLR) and B-cell assay. The N-alkylated fluorinated D-manno-iminosugars 3b/4b were found to be better immunosuppressive agents (IC50=5-6 mu M) on T-cells. The fluorinated iminosugar 3a/4a act as potent and selective inhibitors of beta-glucosidase (IC50= 4-8 mu M). The N-alkyl-iminosugars 4b-c were found to be moderate inhibitors of alpha-glucosidase (yeast) and a-galactosidase (coffee beans), respectively. (C) 2018 Elsevier Ltd. All rights reserved.
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Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem