Kuhl, N; Raval, S; Cohen, RD in [Kuhl, Nadine; Raval, Saurin; Cohen, Ryan D.] Merck & Co Inc, Dept Proc Res & Dev, Rahway, NJ 07065 USA published Synthesis of Cyanamides via a One-Pot Oxidation-Cyanation of Primary and Secondary Amines in 2019, Cited 46. Formula: C7H13NO2. The Name is 1,4-Dioxa-8-azaspiro[4.5]decane. Through research, I have a further understanding and discovery of 177-11-7.
An operationally simple oxidation cyanation method for the synthesis of cyanamides is described. The procedure utilizes inexpensive and commercially available N-chlorosuccinimide and Zn(CN)(2) as reagents to avoid direct handling of toxic cyanogen halides. It is demonstrated to be amenable for the cyanation of a variety of primary and secondary amines and aniline derivatives as well as a complex synthetic intermediate en route to verubecestat (MK-8931). Additionally, kinetic measurements and other control experiments are reported to shed light onto the mechanism of this cyanation reaction.
Formula: C7H13NO2. Bye, fridends, I hope you can learn more about C7H13NO2, If you have any questions, you can browse other blog as well. See you lster.
Reference：
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