1445-73-4, 1-Methyl-4-piperidone is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
In a typical experiment, complex 1 (6.1 mg, 10 tmol) and H[BAr?4].(Et2O)2 (10.1 mg, 10 tmol) were dissolved in THF (2.0 mE) in a 100 mE thick-walled glass vessel equipped with a TEFLON stopcock and a stir bar. The substrate (0.5 mmol) to be hydrogenated was then added. The vessel was degassed by freeze-pump-thaw and then hydrogen (1 or 4 atm) was added. The resulting solution was stirred at the desired temperature (25-60 C.) for the indicated reaction time. At the end of the reaction, the solvent was evaporated and the residue was passed through silica gel in a pipette. The solvent was removed under vacuum and the ?H NMR spectrum of the crude product mixture was recorded in CDC13. Hydrogenation products were then isolated by column chromatography or preparative thin layer chromatography (?TLC?) using n-hexane/ethyl acetate (3:1, v/v) as an eluent. Isolated products were characterized by ?H NMR and GCMS, with spectra matching those reported in the literature or authentic samples., 1445-73-4
The synthetic route of 1445-73-4 has been constantly updated, and we look forward to future research findings.
Reference：
Patent; LOS ALAMOS NATIONAL SECURITY, LLC; Vasudevan, Kalyan V.; Zhang, Guoqi; Hanson, Susan K.; US2015/336862; (2015); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem