140645-24-5, (S)-3-(Aminomethyl)-1-N-Boc-piperidine is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a solution of (S)-tert-hv&y 3-(aminomethyl)piperidine-l-carboxylate (500 mg,2.33 mmol) in CH2CI2 at -10 C was added triethylamine (650 uL, 4.66 mmol) followed by the dropwise addition of 2-methoxyethyl chloroformate (325 uL, 2.79 mmol). The reaction was warmed to room temperature and quenched with water. The aqueous layer was extracted with CH2CI2, and the combined extracts were dried over MgSCU, filtered, and evaporated. Purification via silica gel chromatography using 0 to 10%) EtOAc in CH2CI2 afforded 2-methoxyethyl ((iS)-l-(tert-butoxycarbonyl)piperidin-3-yl)methylcarbamate (496 mg, 67%). LC/MS: m/z 317.3 (M+H)+ at 2.56 min (10%-99% CH3CN (0.035% TFA)/H20 (0.05% TFA)). [001522] 2-Methoxyethyl ((i?)-piperidin-3-yl)methylcarbamate
140645-24-5, 140645-24-5 (S)-3-(Aminomethyl)-1-N-Boc-piperidine 1502022, apiperidines compound, is more and more widely used in various fields.
Reference：
Patent; VERTEX PHARMACEUTICALS INCORPORATED; WO2006/28904; (2006); A1;,
Piperidine – Wikipedia
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