Chemistry is an experimental science, COA of Formula: C11H16N2, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 2359-60-6, Name is 4-Piperidinoaniline
Mutant activin receptor-like kinase-2 (ALK2) was reported to be closely associated with the pathogenesis of fibrodysplasia ossificans progressiva (FOP) and diffuse intrinsic pontine glioma (DIPG), and therefore presents an attractive target for therapeutic intervention. Through in silico virtual screenings and structure?activity relationship studies assisted by X-ray crystallographic analyses, a novel series of bis-heteroaryl pyrazole was identified as potent inhibitors of ALK2 (R206H). Derived from in silico hit compound RK-59638 (6a), compound 18p was identified as a potent inhibitor of ALK2 (R206H) with good aqueous solubility, liver microsomal stability, and oral bioavailability.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. COA of Formula: C11H16N2, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 2359-60-6, in my other articles.
Reference：
Piperidine – Wikipedia,
Piperidine | C5H10584N – PubChem