So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Lee, Yong Ho; Denton, Elliott H.; Morandi, Bill researched the compound: Tris(3,5-bis(trifluoromethyl)phenyl)phosphine( cas:175136-62-6 ).Category: piperidines.They published the article 《Modular Cyclopentenone Synthesis through the Catalytic Molecular Shuffling of Unsaturated Acid Chlorides and Alkynes》 about this compound( cas:175136-62-6 ) in Journal of the American Chemical Society. Keywords: acid chloride unsaturated alkyne internal hydrosilane palladium cyclization catalyst; cyclopentenone preparation. We’ll tell you more about this compound (cas:175136-62-6).
We describe a general strategy for the intermol. synthesis of polysubstituted cyclopentenones using palladium catalysis. Overall, this reaction is achieved via a mol. shuffling process involving an alkyne, an α,β-unsaturated acid chloride, which serves as both the alkene and carbon monoxide source, and a hydrosilane to create three new C-C bonds. This new carbon monoxide-free pathway delivers the products with excellent yields. Furthermore, the regioselectivity is complementary to conventional methods for cyclopentenone synthesis. In addition, a set of regio- and chemodivergent reactions are presented to emphasize the synthetic potential of this novel strategy.
Although many compounds look similar to this compound(175136-62-6)Category: piperidines, numerous studies have shown that this compound(SMILES:FC(C1=CC(C(F)(F)F)=CC(P(C2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)=C1)(F)F), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem