Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent£¬ name: (R)-tert-Butyl 3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate, Which mentioned a new discovery about 1022150-11-3
H based on the quinazoline structure2S donor compound and and its application (by machine translation)
The invention discloses a based on the quinazoline structure H2 S donor compound and and its application, its are of the formula (I) indicated by the compound or its pharmaceutically acceptable salt, wherein Ar is substituted or non-substituted phenyl, substituted ethylenically: halogen, nitro, C1 – 4 Alkyl, C1 – 4 Haloalkyl, C1 – 4 Alkoxy, C1 – 4 Haloalkyl oxy in one or several; X is C1 – 4 Alkoxy, B – NH – or A – CH2 CO – NH – group, Y is H, B – Cn H2n O – or A – Cn H2n O – group, respectively A or B H2 S donor group, n is 1 – 5 integer, and X is C1 – 3 Alkoxyl basetime Y is not H. The present invention is based on the synthesis of a series of 4 – anilinoquinazoline structure of H2 S donor compound, through the H2 S and 4 – anilinoquinazoline derivatives of synergistic effects, thereby improving the antitumor activity of the medicament. (by machine translation)
Because enzymes can increase reaction rates by enormous factors and tend to be very specific, name: (R)-tert-Butyl 3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 1022150-11-3
Reference£º
Piperidine – Wikipedia,
Piperidine | C5H24088N – PubChem