Naruto, Shunsuke published the artcileSynthesis and spasmolytic activity of aminoalkyl 2-substituted 2-(1,2-benzisoxazol-3-yl)acetates, Recommanded Product: 1-Ethylpiperidin-3-ol, the publication is Chemical & Pharmaceutical Bulletin (1987), 35(5), 2095-100, database is CAplus and MEDLINE.
Several aminoalkyl esters (I, II, and III, R = aminoalkyl or alkylpiperidino of 2-(1,2-benzisoxazol-3-yl)-2-cyclohexylacetic acid, 1-(1,2-benzisoxazol-3-yl)-1-cyclopentanecarboxylic acid, and 1-(1,3-benzisoxazol-3-yl)-1-cyclohexanecarboxylic acid and their quaternary ammonium salts were prepared Me 1,2-benzisoxazole-3-acetate was treated with NaH and then cyclohexyl iodide or Br(CH2)4Br or Br(CH2)5Br to give esters which were hydrolyzed and esterified to give I–III, resp. The anticholinergic (anti-Ach) and musculotropic (anti-KCl) activities of these compounds were examined 3-(N,N-Diethylamino)propyl 2-(1,2-benziosoxazol-3-yl)-2-cyclohexylacetate [I, R = (CH2)3NEt2] showed potent anti-Ach and anti-KCl activities.
Chemical & Pharmaceutical Bulletin published new progress about 13444-24-1. 13444-24-1 belongs to piperidines, auxiliary class Piperidine,Alcohol, name is 1-Ethylpiperidin-3-ol, and the molecular formula is C7H15NO, Recommanded Product: 1-Ethylpiperidin-3-ol.
Referemce:
https://en.wikipedia.org/wiki/Piperidine,
Piperidine | C5H11N – PubChem