New basic esters of 3-methyl-4-oxo-2-phenyl-4H-1-benzopyran-8-carboxylic acid endowed with spasmolytic properties: synthesis and pharmacological-pharmacokinetic evaluation was written by Nardi, D.;Leonardi, A.;Pennini, R.;Tajana, A.;Cazzulani, P.;Testa, R.. And the article was included in Arzneimittel-Forschung in 1993.Application In Synthesis of 1-(3-Chloropropyl)piperidine hydrochloride This article mentions the following:
Basic esters of 3-methyl-4-oxo-2-phenyl-4H-1-benzopyran-8-carboxylic acid (I) were prepared as flavoxate analogs. The activity of I esters as spasmolytics was tested and compared to flavoxate. Terflavoxate hydrochloride (II) showed affinity for muscarinic receptors but was devoid of functional antimuscarinic properties. In the experiment, the researchers used many compounds, for example, 1-(3-Chloropropyl)piperidine hydrochloride (cas: 5472-49-1Application In Synthesis of 1-(3-Chloropropyl)piperidine hydrochloride).
1-(3-Chloropropyl)piperidine hydrochloride (cas: 5472-49-1) belongs to piperidine derivatives. The piperidine ring can be found not only in more than half of the currently known structures of alkaloids, but also in many natural or synthetic compounds with interesting biological activities. Piperidine derivatives bearing a masked aldehyde function in the 蔚-position are easily transformed into quinolizidine compounds through intramolecular reductive amination.Application In Synthesis of 1-(3-Chloropropyl)piperidine hydrochloride
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem