Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent£¬ Quality Control of: N-Cbz-4-Piperidinecarboxylic acid, Which mentioned a new discovery about 10314-98-4
Nitrilase-catalyzed enantioselective synthesis of pyrrolidine- And piperidinecarboxylic acids
The enantioselective synthesis of the nonproteinogenic amino acids beta-proline and nipecotic acids from their readily available nitriles is achieved in high enantiomeric excess by commercially available nitrilases. The presented procedure comprises not more than 4 steps, thus considerably reducing the multiple steps generally required. Amide formation is also observed for specific heterocyclic nitriles.
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Reference£º
Piperidine – Wikipedia,
Piperidine | C5H21493N – PubChem