Chemistry, like all the natural sciences, begins with the direct observation of nature¡ª in this case, of matter.120013-39-0, Name is 5,6-Dimethoxy-2-(4-piperidinylmethyl)-1-indanone hydrochloride, SMILES is Cl.COC2=C(C=C1C(C(CC1=C2)CC3CCNCC3)=O)OC, belongs to piperidines compound. In a document, author is Wang, Xue-Juan, introduce the new discover, Application In Synthesis of 5,6-Dimethoxy-2-(4-piperidinylmethyl)-1-indanone hydrochloride.
Tf2O-Promoted Intramolecular Schmidt Reaction of the omega-Azido Carboxylic Acids
A designed Tf2O-promoted intramolecular Schmidt reaction of 2-substituted omega-azido carboxylic acids was demonstrated. Tf2O was used as an activation reagent for the carboxylic acid, and omega-azido anhydride was in situ generated, releasing a molecular TfOH, which acted as an acid promoter for the Schmidt process. A series of 2-substituted pyrrolidines was produced and acetylated for better purification. The strategy was also efficient for conversion of a 4-substituted omega-azido carboxylic acid to the tricyclic lactam.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 120013-39-0 is helpful to your research. Application In Synthesis of 5,6-Dimethoxy-2-(4-piperidinylmethyl)-1-indanone hydrochloride.
Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem