More research is needed about 4,4-Difluoropiperidine

Because enzymes can increase reaction rates by enormous factors and tend to be very specific, Formula: C5H9F2N, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 21987-29-1

Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent£¬ Formula: C5H9F2N, Which mentioned a new discovery about 21987-29-1

Structure-Activity Relationship Studies of Orally Active Antimalarial 2,4-Diamino-thienopyrimidines

Based on the initial optimization of orally active antimalarial 2,4-diamino-thienopyrimidines and with the help of metabolite identification studies, a second generation of derivatives involving changes at the 2- and 4-positions of the thienopyrimidine core were synthesized. Improvements in the physiochemical properties resulted in the identification of 15a, 17a, 32, and 40 as lead molecules with improved in vivo exposure. Furthermore, analogue 40 exhibited excellent in vivo antimalarial activity when dosed orally at 50 mg/kg once daily for 4 days in the Plasmodium berghei mouse model, which is superior to the activity seen with previously reported compounds, and with a slightly improved hERG profile.

Because enzymes can increase reaction rates by enormous factors and tend to be very specific, Formula: C5H9F2N, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 21987-29-1

Reference£º
Piperidine – Wikipedia,
Piperidine | C5H3105N – PubChem