Microwave-promoted amination of 3-bromoisoxazoles was written by Moore, Jane E.;Spinks, Daniel;Harrity, Joseph P. A.. And the article was included in Tetrahedron Letters in 2004.Recommanded Product: 58333-75-8 This article mentions the following:
Amination of 3-bromoisoxazoles, by a nucleophilic aromatic substitution reaction, is described. 3-Bromoisoxazoles were found to be inert to substitution under thermal conditions, however, the employment of phosphazene bases under microwave irradiation facilitated the amination process and allowed 3-aminoisoxazoles, e.g., I, to be isolated in moderate yields. In the experiment, the researchers used many compounds, for example, 4-(2-Methoxyphenyl)piperidine (cas: 58333-75-8Recommanded Product: 58333-75-8).
4-(2-Methoxyphenyl)piperidine (cas: 58333-75-8) belongs to piperidine derivatives. The piperidine ring can be found not only in more than half of the currently known structures of alkaloids, but also in many natural or synthetic compounds with interesting biological activities. Industrially, piperidine is produced by the hydrogenation of pyridine, usually over a molybdenum disulfide catalyst. Pyridine can also be reduced to piperidine via a modified Birch reduction using sodium in ethanol.Recommanded Product: 58333-75-8
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem