In 2022,Ma, Xueji; Wang, Qingyun; Wu, Jinge; Zhang, Liyuan; Sun, Aili; Wang, Zhanyong published an article in Organic & Biomolecular Chemistry. The title of the article was 《NHC-alcohol adduct-mediated photocatalytic deoxygenation for the synthesis of 6-phenanthridine derivatives》.Category: piperidines The author mentioned the following in the article:
NHC-alc. adduct-mediated deoxygenation of alcs. ROH (R = t-Bu, cyclopentyl, N-bocpiperidin-4-yl, etc.) under photocatalytic conditions is described. This process provides various alkyl radicals, which can react with 2-isocyanobiaryls I (R1 = H, Me, F; R2 = H, Cl; R3 = H, MeO, CF3; R4 = H, F, Me, MeO; R5 = H, MeO, CF3; R6 = H, Me, F) to afford 6-substituted phenanthridine derivatives II in moderate to good yields. This method offered the first example of directly using alcs. as radical sources for 6-phenanthridine synthesis. The experimental process involved the reaction of tert-Butyl 4-hydroxypiperidine-1-carboxylate(cas: 109384-19-2Category: piperidines)
tert-Butyl 4-hydroxypiperidine-1-carboxylate(cas:109384-19-2) is a 4-hydroxypyridine with a boc protecting group used in the preparation of neurologically active agents and other pharmaceutical compounds.Category: piperidines
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem