Screening and quantification of pharmaceuticals and their metabolites in municipal wastewater treatment facilities in Guangzhou, China was written by Liu, Zhineng;Rong, Hongwei;Chu, Zhaorui;Luo, Huayong;Zhao, Meihua;Wang, Randeng;Zhang, Chaosheng. And the article was included in Desalination and Water Treatment in 2021.Application of 83799-24-0 The following contents are mentioned in the article:
The combination of qual. methods with quant. anal. of pharmaceuticals and their metabolites in wastewater treatment plants using liquid chromatog. coupled with quadrupole time-of-flight high-resolution mass spectrometry is presented. The selected pharmaceuticals were found at a low or medium level in raw wastewater, compared with previous studies around the world. The removal efficiencies of sulfamethoxazole in the four parallel biol. treatment processes were similar. Data-independent and data-dependent mass spectrometry acquisition methods (All Ions MS/MS and auto MS/MS) were employed for qual. anal. Five of the 18 tentatively identified compounds resulted from data-independent acquisition mode were confirmed with standards Thirty-nine pharmaceuticals and seven metabolites were tentatively identified using data-dependent acquisition mode. The parent pharmaceuticals and their metabolites, such as caffeine and its three metabolites (3-methylxanthine, 1,7-dimethyluric acid, and paraxanthine), were detected in wastewater. Irbesartan and valsartan were tentatively identified in both pos. and neg. modes. The present study demonstrates that both data-dependent and data-independent acquisitions are suitable and reliable for tentative determination of pharmaceuticals and their metabolites in municipal wastewater. This study involved multiple reactions and reactants, such as 2-(4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butyl)phenyl)-2-methylpropanoic acid (cas: 83799-24-0Application of 83799-24-0).
2-(4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butyl)phenyl)-2-methylpropanoic acid (cas: 83799-24-0) belongs to piperidine derivatives. The piperidine structural motif is present in numerous natural alkaloids. These include piperine, which gives black pepper its spicy taste. Piperidine derivatives bearing a masked aldehyde function in the 蔚-position are easily transformed into quinolizidine compounds through intramolecular reductive amination.Application of 83799-24-0
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem